ASSESSMENT OF THE PROLIFERATIVE POTENTIAL OF SHEEP ENDOMETRIAL MESENCHYMAL STEM CELLS

Authors

  • Emoke Pall University of Agricultural Sciences and Veterinary Medicine of Cluj-Napoca, str. Manastur no. 3-5, Cluj-Napoca, Romania Research and Development Institute for Montanology, Cristian – Sibiu, Str. XIII No.147, Cristian, Sibiu, Romania Author
  • Mihai Cenariu University of Agricultural Sciences and Veterinary Medicine of Cluj-Napoca, str. Manastur no. 3-5, Cluj-Napoca, Romania Research and Development Institute for Montanology, Cristian – Sibiu, Str. XIII No.147, Cristian, Sibiu, Romania Author
  • Gheorghita Duca University of Agricultural Sciences and Veterinary Medicine of Cluj-Napoca, str. Manastur no. 3-5, Cluj-Napoca, Romania Research and Development Institute for Montanology, Cristian – Sibiu, Str. XIII No.147, Cristian, Sibiu, Romania Author
  • Marina Spinu University of Agricultural Sciences and Veterinary Medicine of Cluj-Napoca, str. Manastur no. 3-5, Cluj-Napoca, Romania Research and Development Institute for Montanology, Cristian – Sibiu, Str. XIII No.147, Cristian, Sibiu, Romania Author
  • Carmen Dana Sandru University of Agricultural Sciences and Veterinary Medicine of Cluj-Napoca, str. Manastur no. 3-5, Cluj-Napoca, Romania Research and Development Institute for Montanology, Cristian – Sibiu, Str. XIII No.147, Cristian, Sibiu, Romania Author
  • Simona Ciupe University of Agricultural Sciences and Veterinary Medicine of Cluj-Napoca, str. Manastur no. 3-5, Cluj-Napoca, Romania Research and Development Institute for Montanology, Cristian – Sibiu, Str. XIII No.147, Cristian, Sibiu, Romania Author
  • Mihai Borzan University of Agricultural Sciences and Veterinary Medicine of Cluj-Napoca, str. Manastur no. 3-5, Cluj-Napoca, Romania Research and Development Institute for Montanology, Cristian – Sibiu, Str. XIII No.147, Cristian, Sibiu, Romania Author

DOI:

https://doi.org/10.1199/kwkhzf03

Keywords:

endometrial stem cells, multipotency, proliferative potential, regenerative therapy

Abstract

In the recent development of veterinary medicine, stem cell therapy has become increasingly utilized, both in companion animals and livestock. Among the types of stem cells that have garnered researchers' attention are hematopoietic stem cells (HSCs) and mesenchymal stem cells (MSCs). Growing interest is evident in the investigation of the presence and functionality of endometrial cells in farm animals, given their significant potential in the field of reproduction and the treatment of uterine pathologies. Endometrial MSCs it is estimated to have a significant impact on various aspects of veterinary medicine, including transplantation therapy and regenerative medicine. To explore the therapeutic potential of these cells, our study focused on isolating, cultivating, and characterizing endometrial MSCs in sheep. This research makes a significant contribution to an emerging and promising field, providing important insights into the physiology and biology of these cells and contributing to the understanding of reproductive disorders in production animals and the development of new therapeutic modalities.

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Published

2024-08-01

Issue

Vol. 6 No. 3 (2024): Animal Sciences and Veterinary Medicine

Section

Articles